Ta Ma Ra’s friendship started in the spring of 1991, when ,two young PhD students Ivan and François joined Miro Radman's lab on the scientific campus of the Institut Jacques Monod in Jussieu (Paris, France). Miro Radman's scientific life had already a rich history (clik on pre-TaMaRa history) including the discovery of the SOS response, the mechanisms of mismatch repair and the molecular nature of the species barrier.


The lab was relatively small (10-15 people very dynamic people) and poor but they had great fun and their work (evolution of mutators, barriers to horizontal transfer in bacteria, errors in RNA) was well published, attracting interest from the scientitic community at large and even more importantly from young students, colleagues and post-docs. Most of these belonged to the " mutator network " which included 7 labs from 7 different disciplines and which met on a regular basis to exchange ideas and data about the role played by mutator in bacterial evolution (and related topics such as pathogenesis and the emergence of antibiotic resistance) .


After 9 years spent together in Jussieu, which included the PhD of Ivan and François in 1995, Ta Ma Ra’s lab was created in the Necker Children's Hospital Medical School in Paris where it doubled in space and number of people and receive enough funding to start completely new projects. Convinced of the use of Escherichia coli that brought so much to science and so much fun to us, we decided to increase even further the importance of it's genetic analysis by using generic technologies such as fluorescent microscopy that could be applied to investigate many different basic questions about sex, life and death of this model bacteria on an individual basis.


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INSERM/U571 - Laboratoire RADMAN
Université Necker-Enfants Malades - 156, rue de Vaugirard - 75015 Paris FRANCE